Article
Genetic Polymorphisms of the <i>Transforming Growth Factor-β1</i> Gene and Breast Cancer Risk: A Possible Dual Role at Different Cancer Stages
1 Jun 2005
Abstract excerpt
Transforming growth factor-beta (TGF-beta) inhibits the proliferation of carcinomas in early stages of breast cancer, whereas it promotes tumor growth and metastasis in later stages of cancer. We evaluated a possible association between TGF-beta1 gene polymorphisms and breast cancer risk in a population-based case-control study of Chinese women living in Shanghai, which included 1,127 breast cancer cases and...
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