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Genetic Polymorphisms in the <b> <i>TGF-</i> </b>β<b> <i>1</i> </b> Gene and Breast Cancer Survival

1 Feb 2004

Abstract excerpt

The effect of genetic polymorphisms in the TGF-beta1 gene at codon 10 (T+29C), codon 25 (G+74C), and the promoter region [C --> T at -509 from the transcription site, (C-509T)] on breast cancer survival was evaluated among a cohort of 1111 patients. The median follow-up time for the cohort was 5.17 years after cancer diagnosis. No DNA sequence variation at codon 25 of the TGF-beta1 gene was found, whereas...

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PMID: 14871809
DOI: 10.1158/0008-5472.can-03-3492

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