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Article

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms.

Nature cell biology - 1 Aug 2009

Fan Zhipeng, Yamaza Takayoshi, Lee Janice S, Yu Jinhua, Wang Songlin, Fan Guoping, Shi Songtao, Wang Cun-Yu

Abstract excerpt

The BCL-6 co-repressor (BCOR) represses gene transcription by interacting with BCL-6 (Refs 1, 2). BCOR mutation is responsible for oculo-facio-cardio-dental (OFCD) syndrome, which is characterized by canine teeth with extremely long roots, congenital cataracts, craniofacial defects and congenital heart disease. Here we show that BCOR mutation increased the osteo-dentinogenic potential of mesenchymal stem cells...

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Source

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Identifiers

PMID: 19578371
DOI: 10.1038/ncb1913
PMCID: PMC2752141

Genes

BCOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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