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Article

Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.

Journal of experimental & clinical cancer research : CR - 30 Sept 2008

Kasahara Mayumi, Osawa Kayo, Yoshida Kana, Miyaishi Aiko, Osawa Yasunori, Inoue Natsuko, Tsutou Akimitsu, Tabuchi Yoshiki, Tanaka Kenichi, Yamamoto Masahiro, Shimada Etsuji, Takahashi Juro

Abstract excerpt

BACKGROUND: Genetic polymorphisms of DNA repair enzymes may lead to genetic instability and colorectal cancer carcinogenesis. Our objective was to measure the interactions between polymorphisms of repair genes and tobacco smoking in colorectal cancer. METHODS: The case-control study involved sixty-eight colorectal cancer patients and 121 non-cancer controls divided into non-smokers and smokers according to...

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Source

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Identifiers

PMID: 18823566
DOI: 10.1186/1756-9966-27-49
PMCID: PMC2575194

Genes

APEX1
MUTYH
OGG1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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