Article
Significant association of an XRCC4 single nucleotide polymorphism with bladder cancer susceptibility in Taiwan.
Anticancer research - 1 May 2009
Chang Chao-Hsiang, Chang Chia-Lin, Tsai Chia-Wen, Wu Hsi-Chin, Chiu Chang-Fang, Wang Rou-Fen, Liu Chiu-Shong, Lin Cheng-Chieh, Bau Da-Tian
Abstract excerpt
BACKGROUND: The DNA repair gene XRCC4, a member of NHEJ for double strand breaks, is very important in maintaining the overall genome stability, and may play an important role in carcinogenesis. To reveal the relationship between XRCC4 and bladder cancer, seven polymorphic variants of XRCC4, including C-1622T (rs7727691), G-1394T (rs6869366), G-652T (rs2075685), C-571T (rs2075686), intron3 DIP (rs28360071), S247A...