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Article

Transcriptional repression of the IMD2 gene mediated by the transcriptional co-activator Sub1.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2008

Koyama Hiroshi, Sumiya Eriko, Nagata Makiko, Ito Takahiro, Sekimizu Kazuhisa

Abstract excerpt

Sub1 was originally identified as a transcriptional co-activator and later demonstrated to have pleiotropic functions during multiple transcription steps, including initiation, elongation and termination. The present study reveals a novel function of Sub1 as a transcription repressor in budding yeast. Sub1 does not activate IMP dehydrogenase 2 (IMD2) gene expression but rather represses its expression. First, we...

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Source

Identifiers

PMID: 18823333
DOI: 10.1111/j.1365-2443.2008.01229.x

Genes

SUB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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