Article
Signal transduction pathways of mantle cell lymphoma: a phosphoproteome-based study.
Proteomics - 1 Nov 2008
Cecconi Daniela, Zamò Alberto, Bianchi Elena, Parisi Alice, Barbi Stefano, Milli Alberto, Rinalducci Sara, Rosenwald Andreas, Hartmann Elena, Zolla Lello, Chilosi Marco
Abstract excerpt
Mantle cell lymphoma (MCL) is an incurable hematologic malignancy whose pathogenesis is only partly understood. The aim of the present study was to define a "core phosphoproteome" in MCL cell lines that is representative of primary MCL in order to improve knowledge of the signal transduction pathways involved in its tumorigenesis. We have analyzed phosphorylated proteins in several MCL cell lines by immobilized...
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