Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

13 Oct 2010

Abstract excerpt

Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma of which at least a subset arises from antigen-experienced B cells. However, what role antigen stimulation plays in its pathogenesis remains ill defined. The genetic hallmark is the chromosomal translocation t(11;14) resulting in aberrant expression of cyclin D1. Secondary genetic events increase the oncogenic potential of cyclin D1 and frequently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Lymphoma Diagnosis and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20940415
DOI: 10.1182/blood-2010-04-189977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic eraPMID 20940415Read ↗

The molecular pathogenesis of mantle cell lymphoma.Semantic proximity Read ↗

Mantle cell lymphoma: report of the 2010 Mantle Cell Lymphoma Consortium WorkshopSemantic proximity Read ↗

Molecular pathogenesis of mantle cell lymphomaSemantic proximity Read ↗

Mantle cell lymphoma: biology, clinical presentation, and therapeutic approaches.Semantic proximity Read ↗

Mantle cell lymphoma pathology update in the 2016 WHO classificationSemantic proximity Read ↗

Pathogenesis of Mantle-Cell Lymphoma: All Oncogenic Roads Lead to Dysregulation of Cell Cycle and DNA Damage Response PathwaysSemantic proximity Read ↗

Biological and clinical determinants shaping heterogeneity in mantle cell lymphomaSemantic proximity Read ↗

Mantle cell lymphoma: evolving management strategies.Semantic proximity Read ↗

Mantle Cell Lymphoma Under the Scope of Personalized Medicine: Perspective and Directions.Semantic proximity Read ↗

Unraveling MCL biology to understand resistance and identify vulnerabilitiesSemantic proximity Read ↗

[Mantle cell lymphoma: Towards a personalized therapeutic strategy?].Semantic proximity Read ↗

Chronic lymphocytic leukemia and mantle cell lymphoma: crossroads of genetic and microenvironment interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.