Article
Proteogenomic features define subtypes of mantle cell lymphoma.
Blood advances - 26 May 2026
Yan Yuting, Chen Weihao, Ge Xinzhou, Sun Jian, Yu Lei, Garcia-Mansfield Krystine, Zhang Xinyi, Yu Ying, Xiong Wenjie, Zou Dehui, An Gang, Jia Zhenyu, Pirrotte Patrick, Li Jessica Jingyi, Yu Zhen, Hao Mu, Qiu Lugui, Qi Jianwei, Wang Lili, Yi Shuhua
Abstract excerpt
ABSTRACT: Mantle cell lymphoma (MCL) is a biologically heterogeneous B-cell malignancy. Although genomics and transcriptomics have delineated parts of the MCL disease spectrum, proteomics remains largely unexplored. Here, we conducted a comprehensive proteogenomic analysis integrating genomics, transcriptomics, and proteomics on peripheral blood samples from 27 patients with MCL and 4 healthy donors to...
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