Proteome landscape of B-cell malignancies identifies mantle cell lymphoma protein signature

Abstract excerpt

<h4>ABSTRACT</h4> Mantle cell lymphoma (MCL) is one of the deadliest forms of Non-Hodgkin’s B-cell lymphoma. Typically, patients present with both overexpression of CyclinD1 and secondary mutations identified by genomic sequencing. Although MCL patients may initially respond to treatment, they eventually relapse and succumb to disease, highlighting the essential need to identify new targets for treatment. Here we...

Topics

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• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Lymphoma, Mantle-Cell
• Multiomics
• Proteogenomics
• Proteome
• Proteomics
• Transcriptome

Identifiers and source

Literature Corpus work

fa3b6de3-750d-547f-a134-fc5e8e2f2ac3

DOI

10.64898/2026.03.02.709116