Article
unc-3-dependent repression of specific motor neuron fates in Caenorhabditis elegans.
Developmental biology - 15 Nov 2008
Prasad Brinda, Karakuzu Ozgur, Reed Randall R, Cameron Scott
Abstract excerpt
unc-3 encodes the Caenorhabditis elegans ortholog of the Olf-1/Early B cell factor family of transcription factors, which in vertebrates regulate development and differentiation of B lymphocytes, adipocytes, and cells of the nervous system. unc-3 mutants are uncoordinated in locomotion. Here we show that unc-3 represses a VC-like motor neuron program in the VA and VB motor neurons, which in wild-type animals...
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