Article
The small, secreted immunoglobulin protein ZIG-3 maintains axon position in Caenorhabditis elegans.
Genetics - 1 Nov 2009
Bénard Claire, Tjoe Nartono, Boulin Thomas, Recio Janine, Hobert Oliver
Abstract excerpt
Vertebrate and invertebrate genomes contain scores of small secreted or transmembrane proteins with two immunoglobulin (Ig) domains. Many of them are expressed in the nervous system, yet their function is not well understood. We analyze here knockout alleles of all eight members of a family of small secreted or transmembrane Ig domain proteins, encoded by the Caenorhabditis elegans zig ("zwei Ig Domänen") genes....
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