Article
PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans.
Development (Cambridge, England) - 1 Apr 2002
Cameron Scott, Clark Scott G, McDermott Joan B, Aamodt Eric, Horvitz H Robert
Abstract excerpt
During Caenorhabditis elegans development, the patterns of cell divisions, cell fates and programmed cell deaths are reproducible from animal to animal. In a search for mutants with abnormal patterns of programmed cell deaths in the ventral nerve cord, we identified mutations in the gene pag-3, which encodes a zinc-finger transcription factor similar to the mammalian Gfi-1 and Drosophila Senseless proteins. In...
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