Article
Leading edge-secreted Dpp cooperates with ACK-dependent signaling from the amnioserosa to regulate myosin levels during dorsal closure.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2008
Zahedi Baharak, Shen Weiping, Xu Xing, Chen Xi, Mahey Meena, Harden Nicholas
Abstract excerpt
Dorsal closure of the Drosophila embryo is an epithelial fusion in which the epidermal flanks migrate to close a hole in the epidermis occupied by the amnioserosa, a process driven in part by myosin-dependent cell shape change. Dpp signaling is required for the morphogenesis of both tissues, where it promotes transcription of myosin from the zipper (zip) gene. Drosophila has two members of the activated...
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