Article
Regulation of p63 expression in primary and immortalized nasopharyngeal epithelial cells.
International journal of oncology - 1 Oct 2008
Yip Y L, Tsao S W
Abstract excerpt
Mutation of the p53 gene is a common event in human cancer. Interestingly, p53 mutation is uncommon in nasopharyngeal carcinoma (NPC). The DeltaNp63 has been postulated to have a dominant-negative effect on the function of the p53 gene and may play a role in the pathogenesis of nasopharyngeal car...
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