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Article

Regulation of p63 expression in primary and immortalized nasopharyngeal epithelial cells.

International journal of oncology - 1 Oct 2008

Yip Y L, Tsao S W

Abstract excerpt

Mutation of the p53 gene is a common event in human cancer. Interestingly, p53 mutation is uncommon in nasopharyngeal carcinoma (NPC). The DeltaNp63 has been postulated to have a dominant-negative effect on the function of the p53 gene and may play a role in the pathogenesis of nasopharyngeal carcinoma. Immortalization is a common property of cancer cells and is believed to be an early event in carcinogenesis. At...

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Identifiers

PMID: 18813784
DOI: 10.3892/ijo_00000057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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