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Article

Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck

1 Jul 2004

Abstract excerpt

The human p63 gene encodes a series of protein isoforms that differ in their N- and/or C-terminal sequences and possess widely varying activities in promoting or repressing p53-related functions and in regulating the proliferation and differentiation of epithelial cells. To gain further information on the role of p63 expression in human tumours, we used quantitative real-time RT-PCR to study individual p63...

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PMID: 15201986
DOI: 10.3892/ijo.25.1.27

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