Article
[The impact of mtDNA mutations on proteins structure in selected types of cancer].
Postepy biochemii - 1 Jan 2008
Plak Katarzyna, Kukwa Wojciech, Bartnik Ewa, Golik Paweł, Scińska Anna, Krawczyk Tomasz, Czarnecka Anna M
Abstract excerpt
Recently published papers report a large number of mitochondrial DNA mutations in many different cancer types, but their significance for electron transport chain proteins remains unknown. This review covers structural mutations of mitochondrial genes, choosing prostate cancer, esophageal cancer and epithelioma as research models. As all mitochondrial genes encode subunits of the electron transport chain, the...
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