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Article

Epothilone B induces glioblastoma cell death via survivin down-regulation.

Experimental oncology - 1 Sept 2008

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Abstract excerpt

AIM: The clinical resistance of glioblastomas to chemotherapeutic agents can be attributed to drug efflux pumps, such as P-glycoprotein, which contributes to reduce drug efficacy. The present study examined the utility of epothilone B, which is not a substrate for P-glycoprotein, on glioblastoma cells. METHODS: In vitro methods with glioblastoma cells varying in p53 status were used to assess the efficacy of...

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PMID: 18806741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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