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Article

Epirubicin inhibits growth and alters the malignant phenotype of the U‑87 glioma cell line.

Molecular medicine reports - 1 Oct 2015

Wang Xiao-Feng, Zhao Zhe-Feng, Chen Ming-Hui, Yuan Qing-Hua, Li Yong-Li, Jiang Chuan-Lu

Abstract excerpt

Epirubicin, an anthracycline derivative, is one of the main line treatments for brain tumors. The aim of the present study was to verify that epirubicin alters the growth and morphological characteristics of U‑87 glioma cells. In the present study, the effects of epirubicin were tested using cellular and biochemical assays, which demonstrated its anti‑proliferative and cytotoxic effects, with an IC50 of 6.3 µM...

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Source

Identifiers

PMID: 26300546
DOI: 10.3892/mmr.2015.4220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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