Article
An APOA1 promoter polymorphism is associated with cognitive performance in patients with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Feb 2009
Koutsis G, Panas M, Giogkaraki E, Karadima G, Sfagos C, Vassilopoulos D
Abstract excerpt
BACKGROUND: Elevated ApoA1 levels have been associated with decreased dementia risk. The A-allele of the APOA1 -75G/A promoter polymorphism has been associated with elevated ApoA1 levels. OBJECTIVE: We sought to investigate the effect of the APOA1 -75G/A promoter polymorphism on cognitive performance in patients with multiple sclerosis (MS). METHODS: A total of 138 patients with MS and 43 controls were studied...
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