Article
Association between serum paraoxonase 1 activity and its polymorphisms with multiple sclerosis: a systematic review.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Feb 2021
Salari Nader, Rasoulpoor Shna, Hosseinian-Far Amin, Razazian Nazanin, Mansouri Kamran, Mohammadi Masoud, Vaisi-Raygani Aliakbar, Jalali Rostam, Shabani Shervin
Abstract excerpt
BACKGROUND: Human serum paraoxonase (PON) is an enzyme that is synthesized by the liver and enters the bloodstream, and it is transmitted by high-density lipoproteins (HDL). Paraoxonase 1 (PON1) is a hydrolytic enzyme with a wide range of substrates and the ability to protect against lipid oxidation. In this study, due to the activity of PON1 in the brain and its antioxidant effects on the reduction of...
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