Article
Polymorphisms of the endothelial nitric oxide synthase gene in premenopausal women with polycystic ovary syndrome.
Maturitas - 20 Nov 2008
Walch Katharina, Kolbus Andrea, Hefler-Frischmuth Katrin
Abstract excerpt
OBJECTIVES: To investigate the association of two common genetic polymorphisms of the gene encoding for endothelial nitric oxide synthase (Nos3), the enzyme catalyzing the production of nitric oxide (NO), with occurrence of the polycystic ovary syndrome (PCOS). METHODS: In a prospective case-control study, we analyzed 2 polymorphisms of the Nos3 gene cluster (Nos 3 exon 7 Glu298Asp and 27-base pair repeat in...
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