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The Promoter Polymorphism rs3918226 of the Endothelial Nitric Oxide Synthase Gene as a Novel Susceptibility Marker for Peripheral Artery Disease.

Annals of vascular surgery - 1 Nov 2024

Zhabin Sergey, Lazarenko Victor, Azarova Iulia, Klyosova Elena, Bashkatov Daniil, Kononov Stanislav, Dolgintsev Maxim, Churnosov Mikhail, Solodilova Maria, Polonikov Alexey

Abstract excerpt

BACKGROUND: This pilot study aimed to investigate the association between the single nucleotide polymorphism (SNP) rs3918226 in the promoter of the nitric oxide synthase (NOS3) gene and the risk of peripheral artery disease (PAD). METHODS: DNA samples from 1,263 unrelated subjects of Slavic origin, including 620 patients with PAD and 643 controls, were genotyped for the SNP rs3918226 using the MassArray-4 system....

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PMID: 39025213
DOI: 10.1016/j.avsg.2024.05.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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