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Article

Influence of endothelial nitric oxide synthase polymorphisms in psoriasis risk.

Archives of dermatological research - 1 Aug 2011

Coto-Segura Pablo, Coto Eliecer, Mas-Vidal Albert, Morales Blanca, Alvarez Victoria, Díaz Marta, Alonso Belén, Santos-Juanes Jorge

Abstract excerpt

Nitric oxide (NO) is a potent regulator of keratinocyte growth and differentiation that has been implicated in the pathogenesis of psoriasis (Ps). The NOS3 -786 T/C (SNP id rs2070744; http://www.ensembl.org ), intron 4 variable number tandem repeat (VNTR), and Glu298Asp (SNP id rs1799983) polymorphisms, have been associated with differences in NO plasma concentrations and with the risk of hypertension (HT) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21293869
DOI: 10.1007/s00403-011-1129-9

Genes

NOS3
CAD

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