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Article

Lack of phenotype for LTP and fear conditioning learning in calpain 1 knock-out mice.

Neurobiology of learning and memory - 1 Nov 2005

Grammer Michael, Kuchay Shafi, Chishti Athar, Baudry Michel

Abstract excerpt

We previously proposed the hypothesis that calpain activation played an important role in long-term potentiation (LTP) of synaptic transmission in hippocampus. Two forms of calpain are predominant in brain tissues, calpain 1 (mu-calpain), activated by micromolar calcium concentration and calpain 2 (m-calpain), activated by millimolar calcium concentration in vitro. In the present study, we tested the role of...

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Identifiers

PMID: 16150618
DOI: 10.1016/j.nlm.2005.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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