Article
The effect of ABCB1 C3435T polymorphism on pharmacokinetics of tacrolimus in liver transplantation: a meta-analysis.
Gene - 1 Dec 2013
Liu Yuan-Yuan, Li Changping, Cui Zhuang, Fu Xiaomeng, Zhang Shu, Fan Lin-Lin, Ma Jun, Li Guang
Abstract excerpt
OBJECTIVES: The effect of ABCB1 C3435T SNP on the pharmacokinetics of immunosuppressive drug tacrolimus in different studies was conflicting. So a meta-analysis was employed to study the correlation of ABCB1 C3435T SNP and the pharmacokinetics of tacrolimus at different post-transplantation times. METHOD: Several studies about ABCB1 C3435T polymorphism and the pharmacokinetics of tacrolimus were collected through...
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