Article
Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the atherosclerosis risk in communities study.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2008
Morrison Alanna C, Bare Lance A, Luke May M, Pankow James S, Mosley Thomas H, Devlin James J, Willerson James T, Boerwinkle Eric
Abstract excerpt
Ischemic stroke and coronary heart disease (CHD) may share genetic factors contributing to a common etiology. This study investigates whether 51 single nucleotide polymorphisms (SNPs) associated with CHD in multiple antecedent studies are associated with incident ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) study. From the multiethnic ARIC cohort of 14,215 individuals, 495 validated ischemic...
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