Article
Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.
Circulation. Cardiovascular genetics - 1 Apr 2012
Carty Cara L, Buzková Petra, Fornage Myriam, Franceschini Nora, Cole Shelley, Heiss Gerardo, Hindorff Lucia A, Howard Barbara V, Mann Sue, Martin Lisa W, Zhang Ying, Matise Tara C, Prentice Ross, Reiner Alexander P, Kooperberg Charles
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified loci associated with ischemic stroke (IS) and cardiovascular disease (CVD) in European-descent individuals, but their replication in different populations has been largely unexplored. METHODS AND RESULTS: Nine single nucleotide polymorphisms (SNPs) selected from GWAS and meta-analyses of stroke, and 86 SNPs previously associated with myocardial...
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