Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans.

doi:10.1007/s10552-008-9225-7

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Article

Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans.

Cancer causes & control : CCC - 1 Mar 2009

Eom Sang-Yong, Zhang Yan Wei, Kim Sung-Hoon, Choe Kang-Hyeon, Lee Kye Young, Park Jung-Duck, Hong Yun-Chul, Kim Yong-Dae, Kang Jong-Won, Kim Heon

Abstract excerpt

OBJECTIVES: We investigated the association of genetic polymorphisms of NQO1, ALDH2, CYP2E1, and the combined genotype of these genes on lung cancer risk, and also evaluated the association after stratification by cumulative smoking amounts and alcohol drinking levels. METHODS: The case-control s...

Topics

Alcohol Drinking
Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial
Asian People
Case-Control Studies
Cytochrome P-450 CYP2E1
Female
Genetic Predisposition to Disease
Genotype
Humans
Lung Neoplasms
Male
Middle Aged
NAD(P)H Dehydrogenase (Quinone)

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Risk Factors

Smoking

Source

Open in PubMed

Identifiers

PMID: 18798003
DOI: 10.1007/s10552-008-9225-7

Genes

NQO1
ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-18798003-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.