Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China.

doi:10.1016/s0169-5002(01)00182-9

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Article

Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2000

Yin L, Pu Y, Liu T Y, Tung Y H, Chen K W, Lin P

Abstract excerpt

Genetic variations in metabolic activation or detoxification enzymes have been thought to contribute to individual differences in lung cancer susceptibility. Genetic polymorphisms of NAD(P)H quinone oxidoreductase (NQO1), cytochrome P4501A1 (CYP1A1) and microsomal epoxide hydrolase (HYL1) have been associated with increased lung cancer risk in Asian populations. In the present study, the possibility of an...

Topics

Adenocarcinoma
Carcinoma, Squamous Cell
Case-Control Studies
China
Cytochrome P-450 CYP1A1
DNA Primers
DNA, Neoplasm
Epoxide Hydrolases
Female
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung Neoplasms

Male

Middle Aged

NAD(P)H Dehydrogenase (Quinone)

Polymerase Chain Reaction

Polymorphism, Genetic

Smoking

Source

Open in PubMed

Identifiers

PMID: 11551408
DOI: 10.1016/s0169-5002(01)00182-9

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11551408-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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