Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.

doi:10.3346/jkms.2015.30.3.221

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Article

Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.

Journal of Korean medical science - 1 Mar 2015

Kim Jin Hee, Hong Yun-Chul

Abstract excerpt

The role of genetic polymorphisms of NAD(P)H: quinone oxidoreductase 1 (NQO1), which is known to be related to carcinogen metabolism and oxidative status, was evaluated for lung cancer development. The genotypes of two NQO1 polymorphisms, namely, IVS1-27C>G and Ex6+40C>T, were determined in 616 l...

Topics

Aged
Carcinoma, Non-Small-Cell Lung
Female
Genetic Predisposition to Disease
Haplotypes
Humans
Lung Neoplasms
Male
Middle Aged
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Single Nucleotide
Risk
Small Cell Lung Carcinoma
Smoking

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