Article
Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.
Journal of Korean medical science - 1 Mar 2015
Kim Jin Hee, Hong Yun-Chul
Abstract excerpt
The role of genetic polymorphisms of NAD(P)H: quinone oxidoreductase 1 (NQO1), which is known to be related to carcinogen metabolism and oxidative status, was evaluated for lung cancer development. The genotypes of two NQO1 polymorphisms, namely, IVS1-27C>G and Ex6+40C>T, were determined in 616 lung cancer cases and 616 lung cancer-free controls and haplotypes composed of the two polymorphisms were estimated. In...
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