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Article

Association of antipsychotic induced weight gain and body mass index with GNB3 gene: a meta-analysis.

Progress in neuro-psychopharmacology & biological psychiatry - 12 Dec 2008

Souza Renan P, De Luca Vincenzo, Muscettola Giovanni, Rosa Daniela V F, de Bartolomeis Andrea, Romano Silva Marco, Kennedy James L

Abstract excerpt

It has been reported that C825T variant in the gene encoding the G-protein subunit beta3 (GNB3) is associated with antipsychotic-induced weight gain and obesity. We investigated the association of the GNB3 and antipsychotic-induced weight gain as well as body mass index (BMI) using meta-analytical techniques. Our analysis of 402 schizophrenia subjects showed a trend (p=0.072) only under a fixed-model. As it was...

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Source

Identifiers

PMID: 18793692
DOI: 10.1016/j.pnpbp.2008.08.014

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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