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Article

Lipases in the pancreatic beta-cell: implications for insulin secretion.

Biochemical Society transactions - 1 Oct 2008

Fex Malin, Mulder Hindrik

Abstract excerpt

Lipids have been implicated in beta-cell stimulus-secretion coupling. In such a role, lipases in beta-cells would be required to generate lipid coupling factors. We have shown previously that glucose stimulates lipolysis in rodent islets. In addition, lipolysis and diacylglycerol lipase activity in islets are abolished by orlistat, an irreversible lipase inhibitor with a broad specificity for substrates....

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Source

Identifiers

PMID: 18793156
DOI: 10.1042/BST0360885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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