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Article

FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.

Obesity (Silver Spring, Md.) - 1 Nov 2008

Song Yiqing, You Nai-Chieh, Hsu Yi-Hsiang, Howard Barbara V, Langer Robert D, Manson Joann E, Nathan Lauren, Niu Tianhua, F Tinker Lesley, Liu Simin

Abstract excerpt

The FTO gene was recently identified as a susceptibility locus for both obesity and type 2 diabetes by whole-genome association analyses of several European populations. We tested for an association between FTO risk alleles and obesity and diabetes in a well-characterized multiethnic cohort of postmenopausal women in the United States. We genotyped two most significantly associated single-nucleotide polymorphisms...

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Source

Open in PubMed Open full text

Identifiers

PMID: 18787525
DOI: 10.1038/oby.2008.408
PMCID: PMC2732012

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.PMID 18787525Read ↗

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Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population.Semantic proximity Read ↗

Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.Semantic proximity Read ↗

The bigger picture of FTO: the first GWAS-identified obesity gene.Semantic proximity Read ↗

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.Semantic proximity Read ↗

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.Semantic proximity Read ↗

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Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.Semantic proximity Read ↗

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