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Article

Impact of fat mass and obesity-associated (FTO) gene variants on adult obesity and overweight: a comprehensive meta-analysis.

BMC endocrine disorders - 20 Mar 2026

Eghbali Maryam, Iranmanesh Mahta, Hatami Neda, Mobaderi Tofigh, Ghadikolaei Omolbanin Asadi, Cheraghi Sara

Abstract excerpt

OBJECTIVE: Obesity has become one of the most common disorders in the world and causes a significant public health challenge. Genome-wide association studies (GWAS) have identified variants within the FTO gene as an important genetic risk factor for obesity. This study evaluates the associations between FTO gene variants and the risk of obesity in adults. METHOD: In this study, we conducted a comprehensive search...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41862896
DOI: 10.1186/s12902-026-02209-x
PMCID: PMC13122980

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Impact of fat mass and obesity-associated (FTO) gene variants on adult obesity and overweight: a comprehensive meta-analysis.PMID 41862896Read ↗

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The role of fat mass and obesity-associated gene (FTO) in obesity - an overview.Semantic proximity Read ↗

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.Semantic proximity Read ↗

The bigger picture of FTO: the first GWAS-identified obesity gene.Semantic proximity Read ↗

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Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.Semantic proximity Read ↗

Variant rs9939609 in the FTO gene is associated with body mass index among Chinese children.Semantic proximity Read ↗

Genetic variant rs9939609 in FTO is associated with body composition and obesity risk in Korean females.Semantic proximity Read ↗

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