Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.

doi:10.1371/journal.pone.0010521

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.

PloS one - 20 May 2010

Bressler Jan, Kao W H Linda, Pankow James S, Boerwinkle Eric

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in the fat mass and obesity associated (FTO) gene are associated with body mass index (BMI) in populations of European descent. The FTO rs9939609 variant, first detected in a genome-wide association study of diabetes, conferred an increased disease risk that was abolished after adjustment for BMI, suggesting that the association may be due to variation in adiposity. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atherosclerosis

Share to Black or African American

Share to Body Mass Index

Share to Diabetes Mellitus, Type 2

Share to Obesity

Share to Proteins

Share to Quantitative Trait, Heritable

Source

Open in PubMed Open full text

Identifiers

PMID: 20502638
DOI: 10.1371/journal.pone.0010521
PMCID: PMC2873943

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.PMID 20502638Read ↗

FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.Semantic proximity Read ↗

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.Semantic proximity Read ↗

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.Semantic proximity Read ↗

Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study.Semantic proximity Read ↗

Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.Semantic proximity Read ↗

Evaluation of the role of FTO (rs9939609) and MC4R (rs17782313) gene polymorphisms in type 1 diabetes and their relation to obesity.Semantic proximity Read ↗

Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.Semantic proximity Read ↗

Associations of the obesity gene FTO variant with complications and comorbidities in patients with type 1 diabetes.Semantic proximity Read ↗

Common variants of FTO and the risk of obesity and type 2 diabetes in Indians.Semantic proximity Read ↗

The rs7204609 polymorphism in the fat mass and obesity-associated gene is positively associated with central obesity and microalbuminuria in patients with type 2 diabetes from Southern Brazil.Semantic proximity Read ↗

Association of FTO rs9939609 Polymorphism With Obesity and Elevated Glycemic Parameters in a Syrian Population: A Case-Control Study.Semantic proximity Read ↗

FTO Gene rs9939609 is Potentially Associated with Diabetes Related Complications in T2DM Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.