Article
Arterial properties in relation to genetic variations in the adducin subunits in a white population.
American journal of hypertension - 1 Jan 2009
Seidlerová Jitka, Staessen Jan A, Bochud Murielle, Nawrot Tim, Casamassima Nunzia, Citterio Lorena, Kuznetsova Tatiana, Jin Yu, Manunta Paulo, Richart Tom, Struijker-Boudier Harry A, Fagard Robert, Filipovský Jan, Bianchi Giuseppe
Abstract excerpt
BACKGROUND: Adducin is a membrane skeleton protein, which consists of either alpha- and beta- or alpha- and gamma-subunits. We investigated whether arterial characteristics might be related to the genes encoding ADD1 (Gly460Trp-rs4961), ADD2 (C1797T-rs4984), and ADD3 (IVS11+386A>G-rs3731566). METHODS: We randomly recruited 1,126 Flemish subjects (mean age, 43.8 years; 50.3% women). Using a wall-tracking...
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