Article
Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population.
Journal of hypertension - 1 Jun 2008
Kuznetsova Tatiana, Citterio Lorena, Herbots Lieven, Carpini Simona Delli, Thijs Lutgarde, Casamassima Nunzia, Richart Tom, Fagard Robert H, Bianchi Giuseppe, Staessen Jan A
Abstract excerpt
BACKGROUND: We investigated the possible association between left ventricular diastolic function and the ADD1 Gly460Trp and ADD3 IVS11 +386A>G polymorphisms alone and in combination. METHODS: In a family-based population study (473 subjects; 50.5% women; mean age 50.5 years), we measured early (Ea) and late (Aa) diastolic peak velocities of the mitral annulus by tissue Doppler imaging. In multivariate-adjusted...
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