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Article

A study of collectin genes in spontaneous preterm birth reveals an association with a common surfactant protein D gene polymorphism.

Pediatric research - 1 Jan 2012

Karjalainen Minna K, Huusko Johanna M, Tuohimaa Anu, Luukkonen Aino, Haataja Ritva, Hallman Mikko

Abstract excerpt

INTRODUCTION: Preterm birth is the major cause of mortality and morbidity in neonates. Intrauterine infection and/or inflammatory response are evident in 60-70% of spontaneous preterm births (SPTBs). Genetic factors significantly increase this risk. However, the genetic background associated with SPTB is poorly understood. Surfactant protein (SP) A, SP-D, and mannose-binding lectin (MBL) are structurally and...

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Source

Identifiers

PMID: 22289856
DOI: 10.1038/pr.2011.2

Genes

SPTB
SFTPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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