Article
Assessing the prognostic role of ATR mutation in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study.
Gynecologic oncology - 1 Sept 2015
Zighelboim Israel, Ali Shamshad, Lankes Heather A, Backes Floor, Moore Kathleen, Mutch David, Robison Katina, Behbakht Kian, Waggoner Steven, Ghebre Rahel G, Pearl Michael, Ramirez Nilsa C, Goodfellow Paul
Abstract excerpt
OBJECTIVE: We sought to validate the clinicopathologic implications and prognostic significance of ATR (ataxia telangiectasia mutated and Rad3-related) mutation in patients with endometrioid endometrial cancer and defective DNA mismatch repair enrolled in a cooperative group molecular staging study of endometrial cancer. METHODS: After pathology review, only endometrioid tumors with high neoplastic cellularity...
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