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Methylation of <i>APC, TIMP3</i>, and <i>TERT</i>: a new predictive marker to distinguish Barrett's oesophagus patients at risk for malignant transformation

8 Nov 2005

Abstract excerpt

Barrett's associated oesophageal adenocarcinoma (EAC) is one of the most rapidly increasing malignancies in Western countries. Because of its poor prognosis, management of this disease through screening of Barrett's oesophagus (BE) patients and identification of those with a high risk of developing an adenocarcinoma seems a promising approach. Early molecular markers of malignant transformation might contribute...

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PMID: 16278815
DOI: 10.1002/path.1884

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