Article
Status and significance of CpG island methylator phenotype in endometrial cancer.
Gynecologic and obstetric investigation - 1 Jan 2011
Zhang Qing-Ying, Yi De-Qing, Zhou Li, Zhang Dong-Hong, Zhou Tai-Mei
Abstract excerpt
BACKGROUND: Endometrial cancer is a common gynecologic malignant disease, but patients with advanced disease have a poor prognosis. The CpG island methylator phenotype (CIMP) involves hypermethylation targeted toward the promoters of multiple genes. OBJECTIVE: To investigate the role of epigenetic aberration of tumor-related genes in endometrial cancer. METHODS: The promoter methylation status of 5 genes was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
