Article
Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.
The Journal of biological chemistry - 14 Nov 2008
Cunha Shane R, Mohler Peter J
Abstract excerpt
Ankyrin-B targets ion channels and transporters in excitable cells. Dysfunction in ankyrin-B-based pathways results in defects in cardiac physiology. Despite a wealth of knowledge regarding the role of ankyrin-B for cardiac function, little is known regarding the mechanisms underlying ankyrin-B regulation. Moreover, the pathways underlying ankyrin-B targeting in heart are unclear. We report that alternative...
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