Article
The evolving role of ankyrin-B in cardiovascular disease.
Heart rhythm - 1 Dec 2017
Koenig Sara N, Mohler Peter J
Abstract excerpt
Over the past decade, ankyrin-B has been identified as a prominent player in cardiac physiology. Ankyrin-B has a multitude of functions, with roles in expression, localization, and regulation of proteins critical for cardiac excitability, cytoskeletal integrity, and signaling. Furthermore, human ANK2 variants that result in ankyrin-B loss of function are associated with "ankyrin-B syndrome," a complex cardiac...
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