Article
Maternal undernutrition programmes atherosclerosis in the ApoE*3-Leiden mouse.
The British journal of nutrition - 1 Apr 2009
Yates Zoe, Tarling Elizabeth J, Langley-Evans Simon C, Salter Andrew M
Abstract excerpt
Poor quality of nutrition during fetal development is associated with adverse health outcomes in adult life. Epidemiological studies suggest that markers of fetal undernutrition are predictive of risk of the metabolic syndrome and CHD. Here we show that feeding a low-protein diet during pregnancy programmed the development of atherosclerosis in ApoE*3-Leiden mice. ApoE*3-Leiden mice carry a mutation of human...
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