Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE-/- mice.

Clinical science (London, England : 1979) - 1 Aug 2012

Blackmore Heather L, Piekarz Ana V, Fernandez-Twinn Denise S, Mercer John R, Figg Nichola, Bennett Martin, Ozanne Susan E

Abstract excerpt

Numerous animal studies have consistently shown that early life exposure to LP (low-protein) diet programmes risk factors for CVD (cardiovascular disease) such as dyslipidaemia, high BP (blood pressure) and cardiac dysfunction in the offspring. However, studies on the effect of maternal under-nutrition on offspring development of atherosclerosis are scarce. Applying our LP model to the ApoE(-/-)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Diet, Protein-Restricted

Share to Malnutrition

Share to Maternal Nutritional Physiological Phenomena

Share to Prenatal Exposure Delayed Effects

Share to Receptors, LDL

Source

Open in PubMed Open full text

Identifiers

PMID: 22375564
DOI: 10.1042/CS20110487
PMCID: PMC3341090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE-/- mice.PMID 22375564Read ↗

Maternal undernutrition programmes atherosclerosis in the ApoE*3-Leiden mouse.Semantic proximity Read ↗

Maternal Phytosterol Supplementation during Pregnancy and Lactation Modulates Lipid and Lipoprotein Response in Offspring of apoE-Deficient Mice.Semantic proximity Read ↗

Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models.Semantic proximity Read ↗

Do the Apoe-/- and Ldlr-/- Mice Yield the Same Insight on Atherogenesis?Semantic proximity Read ↗

Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice.Semantic proximity Read ↗

Maternal hypercholesterolemia exacerbates atherosclerosis lesions in female offspring through potentiating macrophage polarization toward an inflammatory M1 phenotype.Semantic proximity Read ↗

Genetic Modifiers of Atherosclerosis in MiceSemantic proximity Read ↗

The fetal origins of atherosclerosis: maternal hypercholesterolemia, and cholesterol‐lowering or antioxidant treatment during pregnancy influence in utero programming and postnatal susceptibility to atherogenesisSemantic proximity Read ↗

Intrauterine Exposure to Maternal Atherosclerotic Risk Factors Increases the Susceptibility to Atherosclerosis in Adult LifeSemantic proximity Read ↗

Prenatal exposure to a low-protein diet programs disordered regulation of lipid metabolism in the aging ratSemantic proximity Read ↗

Perinatal Hypercholesterolemia Exacerbates Atherosclerosis Lesions in Offspring by Altering Metabolism of Trimethylamine-N-Oxide and Bile Acids.Semantic proximity Read ↗

Mouse models of disturbed HDL metabolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.