Cell type-specific DNA methylation patterns in the human breast.

doi:10.1073/pnas.0805206105

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Article

Cell type-specific DNA methylation patterns in the human breast.

Proceedings of the National Academy of Sciences of the United States of America - 16 Sept 2008

Bloushtain-Qimron Noga, Yao Jun, Snyder Eric L, Shipitsin Michail, Campbell Lauren L, Mani Sendurai A, Hu Min, Chen Haiyan, Ustyansky Vadim, Antosiewicz Jessica E, Argani Pedram, Halushka Marc K, Thomson James A, Pharoah Paul, Porgador Angel, Sukumar Saraswati, Parsons Ramon, Richardson Andrea L, Stampfer Martha R, Gelman Rebecca S, Nikolskaya Tatiana, Nikolsky Yuri, Polyak Kornelia

Abstract excerpt

Cellular identity and differentiation are determined by epigenetic programs. The characteristics of these programs in normal human mammary epithelium and their similarity to those in stem cells are unknown. To begin investigating these issues, we analyzed the DNA methylation and gene expression profiles of distinct subpopulations of mammary epithelial cells by using MSDK (methylation-specific digital karyotyping)...

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Identifiers

PMID: 18780791
DOI: 10.1073/pnas.0805206105
PMCID: PMC2532972

Genes

BMP4
FOXC1
HOXA10
TCF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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