Article
Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2012
Park So Yeon, Kwon Hyeong Ju, Choi Yoomi, Lee Hee Eun, Kim Sung-Won, Kim Jee Hyun, Kim In Ah, Jung Namhee, Cho Nam-Yun, Kang Gyeong Hoon
Abstract excerpt
Although DNA methylation profiles in breast cancer have been connected to breast cancer molecular subtype, there have been no studies of the association of DNA methylation with stem cell phenotype. This study was designed to evaluate the promoter CpG island methylation of 15 genes in relation to breast cancer subtype, and to investigate whether the patterns of CpG island methylation in each subtype are associated...
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