Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brief Reports: A Distinct DNA Methylation Signature Defines Breast Cancer Stem Cells and Predicts Cancer Outcome

28 Jul 2014

Abstract excerpt

Self-renewal and differentiation are two epigenetic programs that regulate stem cells fate. Dysregulation of these two programs leads to the development of cancer stem cells (CSCs). Recent evidence suggests that CSCs are relatively resistant to conventional therapies and responsible for metastasis formation. Deciphering these processes will help understand oncogenesis and allow the development of new targeted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Epigenetics and DNA Methylation
Share to Genomics and Chromatin Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25069843
DOI: 10.1002/stem.1792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brief Reports: A Distinct DNA Methylation Signature Defines Breast Cancer Stem Cells and Predicts Cancer OutcomePMID 25069843Read ↗

Epigenetic Regulation of Breast Cancer Stem Cells Contributing to Carcinogenesis and Therapeutic ImplicationsSemantic proximity Read ↗

Cell type-specific DNA methylation patterns in the human breast.Semantic proximity Read ↗

Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes.Semantic proximity Read ↗

Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cellsSemantic proximity Read ↗

Regional methylome profiling reveals dynamic epigenetic heterogeneity and convergent hypomethylation of stem cell quiescence-associated genes in breast cancer following neoadjuvant chemotherapySemantic proximity Read ↗

Genetic and epigenetic analysis of putative breast cancer stem cell modelsSemantic proximity Read ↗

Concise Review: Breast Cancer Stem Cells: Regulatory Networks, Stem Cell Niches, and Disease RelevanceSemantic proximity Read ↗

Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progressionSemantic proximity Read ↗

Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem CellsSemantic proximity Read ↗

Epigenetic patterns of embryonic and adult stem cellsSemantic proximity Read ↗

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone ModificationsSemantic proximity Read ↗

The transcriptional landscape of cancer stem-like cell functionality in breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.