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Article

EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway.

The Journal of biological chemistry - 31 Oct 2008

Klein Stéphanie, Partisani Mariagrazia, Franco Michel, Luton Frédéric

Abstract excerpt

We have previously reported that EFA6, exchange factor for Arf6, is implicated upon E-cadherin engagement in the process of epithelial cell polarization. We had found that EFA6 acts through stabilization of the apical actin ring onto which the tight junction is anchored. Mutagenesis experiments s...

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Identifiers

PMID: 18779331
DOI: 10.1074/jbc.M803375200
PMCID: PMC2662076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18779331-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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